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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
publication
Title:
Toxicity of ditertiarybutyl-methylphenol.
Author:
Deichmann et al.
Year:
1955
Bibliographic source:
AMA Arch Ind Health. Feb;11(2): 93-101.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Acute Toxicity Oral
Principles of method if other than guideline:
Acute Toxicity Oral
GLP compliance:
not specified
Test type:
other: Acute Toxicity Oral

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-di-tert-butyl-p-cresol
EC Number:
204-881-4
EC Name:
2,6-di-tert-butyl-p-cresol
Cas Number:
128-37-0
Molecular formula:
C15H24O
IUPAC Name:
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-
Details on test material:
component substance

Results and discussion

Any other information on results incl. tables

LD50 (oral, rats) >1700 -1970 mg/kg bw;

 

Approximate lethal dose:

Cats, oral =940-2100 mg/kg bw;

Rabbits, oral =2100-3200 mg/kg bw;

Guinea pig, oral=10700 mg/kg bw.

Applicant's summary and conclusion

Conclusions:
Acute toxicity data on components