Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
publication
Title:
Toxicity of ditertiarybutyl-methylphenol.
Author:
Deichmann et al.
Year:
1955
Bibliographic source:
AMA Arch Ind Health. Feb;11(2): 93-101.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Acute Toxicity Oral
Principles of method if other than guideline:
Acute Toxicity Oral
GLP compliance:
not specified
Test type:
other: Acute Toxicity Oral

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-di-tert-butyl-p-cresol
EC Number:
204-881-4
EC Name:
2,6-di-tert-butyl-p-cresol
Cas Number:
128-37-0
Molecular formula:
C15H24O
IUPAC Name:
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-
Details on test material:
component substance

Results and discussion

Any other information on results incl. tables

LD50 (oral, rats) >1700 -1970 mg/kg bw;

 

Approximate lethal dose:

Cats, oral =940-2100 mg/kg bw;

Rabbits, oral =2100-3200 mg/kg bw;

Guinea pig, oral=10700 mg/kg bw.

Applicant's summary and conclusion

Conclusions:
Acute toxicity data on components