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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
publication
Title:
Acute toxicological evaluation of butylated hydroxytoluene.
Author:
Bomhard
Year:
1996
Bibliographic source:
Journal oft he American College of Toxicology, vol. 15 (suppl.)

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-di-tert-butyl-p-cresol
EC Number:
204-881-4
EC Name:
2,6-di-tert-butyl-p-cresol
Cas Number:
128-37-0
Molecular formula:
C15H24O
IUPAC Name:
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-
Details on test material:
substance component

Results and discussion

Any other information on results incl. tables

Study results:

 

The test substance was slightly irritating to the intact and abraded skin of the rabbit.

Applicant's summary and conclusion

Conclusions:
Skin irritation data on component