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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

A measured BCF is not available for hexadecene. Log BCFs have been calculated on the basis of a log Kow value of 7.98 using two QSARs. Calculated log BCFs range from 3.05 - 4.41.

Key value for chemical safety assessment

Additional information

A measured BCF is not available for hexadecene. As the calculated log Kow of hexadecene is >3 the bioaccumulation endpoint cannot be waived. However, ECHA's Guidance on Information Requirements and Chemical Safety Assessment R7c Endpoint Specific Guidance (2008) indicates that before commissioning a new vertebrate test alternative sources of data on the bioaccumulation potential of a chemical should be used.

Nonpolar substances have been shown to have a linear relationship between log Kow and BCF in the log Kow range 1 - 6. However, at log Kow >6 a decreasing relationship is observed. Several QSARs have been developed that calculate the BCF of non-polar, hydrophobic compounds on the basis of their log Kow (e.g. Connell and Hawker, 1988, USEPA, 2008). Hexadecene falls within the applicability domain of these models. The calculated log BCFs range from 3.05 - 4.41, indicating that hexadecene may bioaccumulate or pose a risk of secondary poisoning.