Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The substance Titanium complexes of ammonium lactate, triisopropanolamine and polyethylene glycol, has been tested and this demonstrates the limited toxicity of this class of substance, even though it is questionably whether aquatic studies should have been attempted for this substance without pre-hydrolysing in accordance with OECD guideline 23 on testing of difficult substances. Alcoholamines are considered to be the most environmentally hazardous of the degradation products and this diethanolamine is more biologically active than the triisopropanolamine released from hydrolysis. Data on this substance suggests low toxicity and questions the data from the NONS submission that uses measured concentrations. 


Reporting ‘measured concentrations’ based on titanium in water only in the NONS summary data will very likely result in much lower concentrations than the nominal concentrations. Analysis should have been performed on a stable water soluble organic metabolite to provide a more accurate indication. It is considered that the algal and Daphnia reproduction studies cannot be reliably assessed from the NONS summaries provided by ECHA under the 12 year rule.