Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Read-across justification summary is attached to this endpoint summary.

Short description of key information:
Dienone did not show a mutagenic potential in a bacterial reverse mutation assay (Salmonella typhimurium: TA1535, TA1537, TA98, TA100 and Echerichia coli: WP2 (pKM101), WP2 uvrA (pKM101)) when tested up to the highest recommended dose level of 5.0 mg/plate in the absence or presence of extrinsic metabolic activation (rat liver S9 mix). Therefore, by read-across, didenac is not mutagenic.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Based on read-across to dienone, didenac is not classified as mutagenic according to the Directive 67/548/EEC or according to Regulation (EC) 1272/2008 (CLP).