Registration Dossier
Registration Dossier
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EC number: 411-380-6 | CAS number: 147315-50-2 CG 30-1577
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD method, GLP compliance
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD GUIDELINE 402 (84/449/EEC B.3)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-((hexyl)oxy)phenol
- EC Number:
- 411-380-6
- EC Name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-((hexyl)oxy)phenol
- Cas Number:
- 147315-50-2
- Molecular formula:
- C27H27N3O2
- IUPAC Name:
- 2-(4,6-diphenyl-1,3,5-triazin-2-yl)-5-(hexyloxy)phenol
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Type of coverage:
- semiocclusive
- Vehicle:
- other: 0.5% (w/v) carboxymethylcellulose in 0.1% (w/v) aqueous polysorbate 80.
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 1 333 mg/kg bw
- Mortality:
- Male: 1333 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 1333 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: COMMEN SYMPTOMS IN ACUTE TESTS (PILOERECTION, ABNORMAL BODY POSITION AND DYSPNEA). ALL ANIMALS RECOVERED WITHIN 2 DAYS.
- Gross pathology:
- Effects on organs:
NONE
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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