Registration Dossier

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature.

Data source

Reference
Title:
Unnamed
Year:
1988

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Thionyl dichloride
EC Number:
231-748-8
EC Name:
Thionyl dichloride
Cas Number:
7719-09-7
Molecular formula:
Cl2 O S
IUPAC Name:
thionyl dichloride
Details on test material:
TS-Freetext:
Thionyl chloride, CAS No. 7719-09-7; no further data

Method

Species / strain
Species / strain / cell type:
other: Salmonella typhimurium TA98, TA100, TA1535, TA1537
Metabolic activation:
with and without
Test concentrations with justification for top dose:
no data
Details on test system and experimental conditions:
IUCLID4 Type: Ames test

Results and discussion

Test results
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified
Remarks on result:
other: other: Salmonella typhimurium TA98, TA100, TA1535, TA1537
Remarks:
Migrated from field 'Test system'.

Applicant's summary and conclusion