Registration Dossier
Registration Dossier
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EC number: 609-333-1 | CAS number: 37143-54-7
PBT assessment
Administrative data
Assessed Substance
- Assessed substance:
- substance itself
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- 609-333-1
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 609-333-1]
- CAS number:
- 37143-54-7
- Identity:
- Reaction mass of (R)-(-)-1-methoxy-2-propylamine and (S)-(+)-1-methoxy-2-propylamine
- Molecular formula:
- C4 H11 N O
- Molecular weight:
- 89.137
Referenceopen allclose all
- Name:
- 1-methoxy-2-propanamine
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- 1-methoxy-2-propanamine
- Reference substance:
- 1-methoxy-2-propanamine
- Name:
- 1-methoxy-2-propanamine
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- 1-methoxy-2-propanamine
- Reference substance:
- 1-methoxy-2-propanamine
Results of detailed PBT / vPvB assessment
Persistence
Evidence of non-P / non-vP properties
Screening criteria
Criteria based on Annex XIII of REACH
Evidence of P or vP properties
- Remark:
- The substance fulfills the screening criteria for P/vP.
Conclusion
- Conclusion on P / vP properties:
- No conclusion can be reached based on available information
Bioaccumulation
Evidence of non-B / non-vB properties
Screening criteria
- Not B and not vB based on: Log Kow ≤ 4.5
- Remark:
- Due to the very low n-octanol/water distribution coefficient (log Pow) of the substance an accumulation in organisms is not to be expected.
Criteria based on Annex XIII of REACH
Conclusion
- Conclusion on B / vB properties:
- not B/vB
Toxicity
Evidence of non-T properties
Criteria based on Annex XIII of REACH
- Not T based on:
- EC10 or NOEC ≥ 0.01 mg/L for marine / freshwater organisms (long-term toxicity):
- No aquatic long-term tests are available and necessary.
- and substance is not classified as carcinogenic (category 1 or 2), mutagenic (category 1 or 2), or toxic for reproduction (category 1, 2 or 3) according to Directive 67/548/EEC or carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) according to Regulation EC No 1272/2008:
- The substance is not classified in any of the categories mentioned above.
- and no other evidence of chronic toxicity, as identified by the classifications T, R48 or Xn, R48 according to Directive 67/548/EEC or specific target organ toxicity after repeated exposure (STOT RE category 1 or 2) according to Regulation EC No 1272/2008:
- The substance is not classified in any of the categories mentioned above.
Further information for the PBT assessment is necessary
- Remark:
- Acute studies on three trophic levels are available. All short-term endpoints were well above the trigger of 0.1 mg/L
Evidence of T properties
Conclusion
- Conclusion on T properties:
- not T
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