Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The determination of vapour pressure follows the OCDE guideline, the test was realised under GLP compliance. No deviation from the guideline were stated.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
2007-01-12
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Constituent 1
Reference substance name:
acetalization product between glucose and C14 alcohol
EC Number:
923-418-3
IUPAC Name:
acetalization product between glucose and C14 alcohol
Details on test material:
Test item: batch no.T82925
Appearence: white pellets
storage: at room temperature 20 +/- 5°C, dark

Results and discussion

Vapour pressureopen allclose all
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0.003 Pa
Temp.:
ca. 25 °C
Vapour pressure:
ca. 0.006 Pa

Applicant's summary and conclusion

Conclusions:
The test item has a calculated vapour pressure:
2.90E-03 Pa at 20°C
6.1E-03 Pa at 25°C
Executive summary:

Introduction

Dtermination of the vapour pressure of the test item was done according to OCDE 104 resp. EU A.4.

Method

The method is based on the estimation of the mass of test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of effused vapour can be obtained either by determining the loss of mass of the cell or by condensing the vapour at low temperature and determining the amount of volatilized substance using chromatography. The vapour pressure is calculated by applying the Hertz-Knudsen relation with correction factors that depend on parameters of the apparatus.

Conclusion

The test item has a calculated vapour pressure:

2.90E-03 Pa at 20°C

6.1E-03 Pa at 25°C