Registration Dossier
Registration Dossier
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EC number: 922-114-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is a hydrocarbon UVCB. Standard tests for this endpoint are intended for single substances and are not appropriate for this complex substance. However this endpoint is characterised for representative hydrocarbon substances that comprise the hydrocarbon block(s) used to assess the environmental risk of this substance with the PETRORISK model.
However, there are reliable data available considered suitable for read-across using the analogue approach and which are reported here in addition.The target substance is a hydrocarbon solvent with carbon numbers in the range of C5 to C6. The main constituents of the mixed solvent consist of about 43% of C6 species and about 57% of C5 species. n-Hexane is only present in concentrations < 5% of the total volume.
Taking into account all available data, animal and human toxicity data as well as environmental fate and effects data show that source substances have a similar (eco-)toxicological and environmental fate properties as the target substance.
Therefore, read-across is performed based on an analogue approach (for details please refer to the analogue justification which is attached in section 13 of the technical dossier).
A BCF was calculated for hydrocarbons, C6, isoalkanes, <5% n-hexane and pentane by Veith and Broderius (1987) using a QSAR, based on a log Kow of 3.6 and 3.45, respectively. The QSAR used to calculate the BCF followed the TGD guideline and so is deemed suitable for the assessment of bioconcentration. Based on an analogue approach the calculated BCFs of 501.187 and 171 for Hydrocarbons, C6, isoalkanes, <5% n-hexane and pentane, respectively, indicate that Hydrocarbons, C5-C6, n-alkanes, isoalkanes, <5% n-hexane does not greatly bioaccumulate in the lipids of ecological receptors.
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