Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 220-860-2 | CAS number: 2920-38-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
A SAR/(Q)SAR prediction performed with the OECD toolbox 2.2 (2011) based on an existing Danish EPA DB (Q)SAR model for skin sensitisation revealed no protein binding alerts in the parent structure. There were no data available for a category approach based on the relevant functional groups (arene, biphenyl, and nitrile).
In general, experimental data is considered to be more relevant than a theoretical prediction model. Nevertheless, based on OECD Toolbox prediction using Danish EPA DB (Q)SAR model for skin sensitisation, a skin sensitisation potential of the test item is not expected.
As seen on the ECHA dissemination view, neither benzontrile nor biphenyl are sensitizing. It is therefore unlikely that the p-phenylbenzotrile is sensitizing to skin.
Migrated from Short description of key information:
There are no data available concerning skin sensitisation. A SAR/(Q)SAR prediction of the test substance for skin sensitisation performed with the OECD Toolbox 2.2 (2011) affilliating an existing (Q)SAR model for skin sensitisation of the Danish EPA DB indicated no skin sensitising potential of the target substance.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data available.
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
There are no experimental test data available for skin sensitisation. Based on OECD Toolbox prediction using Danish EPA DB (Q)SAR model for skin sensitisation, a skin sensitisation potential of the test item is not expected. Therefore, classification for skin sensitisation under Directive 67/548/EEC is not warranted.
Classification, Labeling, and Packaging Regulation (EC) No. 1272/2008
There are no experimental test data available for skin sensitisation. Based on OECD Toolbox prediction using Danish EPA DB (Q)SAR model for skin sensitisation, a skin sensitisation potential of the test item is not expected. Therefore, classification for skin sensitisation under Regulation (EC) No.1272/2008 is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
