Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26 April - 23 May 2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to an appropriate EU test method and in compliance with GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report date:
2007

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.16 (Relative Self-Ignition Temperature for Solids)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
480-420-2
EC Name:
-
Cas Number:
144702-27-2
Molecular formula:
C33 H29 N5
IUPAC Name:
4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl]-2-carbonitrile
Details on test material:
- Name of test material (as cited in study report): BIBR 277 Nitril
- Molecular formula (if other than submission substance): C33H29N5
- Molecular weight (if other than submission substance): 495.6 g/mol
- Structural formula attached as image file (if other than submission substance): see reference substance
- Physical state: solid; white
- Analytical purity: 99.7 %
- Purity test date: 27. march 2007
- Lot/batch No.: 80A
- Expiration date of the lot/batch: 8 march 2008
- Storage condition of test material: at room temperature, dark and dry

Results and discussion

Any other information on results incl. tables

No self-ignition temperature of the test substance was observed up to 197°C (melting point was determined to be 197°C).

Applicant's summary and conclusion

Conclusions:
No self-ignition of the test substance was observed up to the maximum temperature of 400°C.