Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: scientifically accepted calculation method

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Guideline:
other: calcilation
Principles of method if other than guideline:
calculation program: KOWIN v. 1.68
GLP compliance:
no
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenylephrine
EC Number:
200-424-8
EC Name:
Phenylephrine
Cas Number:
59-42-7
Molecular formula:
C9H13NO2
IUPAC Name:
3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.21
Temp.:
25 °C

Applicant's summary and conclusion