Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Modern GLP study peformed on the basis of EC directive 92/69/EEC A.2.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Principles of method if other than guideline:
Not applicable.
GLP compliance:
yes
Type of method:
method according to Siwoloboff

Test material

Constituent 1
Reference substance name:
PTH-Decahydroamide
IUPAC Name:
PTH-Decahydroamide
Constituent 2
Reference substance name:
Ro 31-9373/000
IUPAC Name:
Ro 31-9373/000
Details on test material:
The test material received from F. Hoffmann-La Roche Ltd was a white solid powder from lot no. 25927 with a purity of 99.8%.

Results and discussion

Boiling point
Boiling pt.:
364.8 °C

Any other information on results incl. tables

TABLE 1 - BOILING TEMPERATURE OF PTH-DECAHYDROAMIDE

Boiling Temperature at atmospheric pressure (⁰C)

Atmospheric pressure (kPa)

Boiling Temperature corrected for normal atmospheric pressure (⁰C)

363.5

101.60

363.35

364.5

96.59

366.45

362.8

96.59

364.65

 

Average

364.8

 

Std dev.

1.56 (n=3)

 

Relative std dev.

0.4%

The mean boiling point was determined to be 364.8 ⁰C. At a temperature near 300 ⁰C the test substance turned to a yellow-brown colour.

Applicant's summary and conclusion

Conclusions:
The mean boiling point was determined to be 364.8 ⁰C. At a temperature near 300 ⁰C the test substance turned to a yellow-brown colour.
Executive summary:

The boiling point of PTH-decahydroamide was obtained using the EU method A.2. The mean boiling point was determined to be 364.8 ⁰C. At a temperature near 300 ⁰C the test substance turned to a yellow-brown colour.