Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
In accordance with Column 2 of REACH Annex VII, the in vivo skin sensitisation study (required in Section 8.3) does not need to be conducted as the available information indicates that GLS-Silane meets the criteria for classification as corrosive to skin. In addition, available data for one of the primary constituents in GLS-Silane, tetramethylsilane - CAS 75-76-3, which is present in GLS-Silane at a concentration of 10 - 30%, showed no sensitization in guinea pigs in a GLP study completed according to OECD Guideline 406.

Justification for classification or non-classification

There are no data to suggest that GLS-Silane should be classified for skin or respiratory sensitisation.