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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP. Guideline study

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method C.3 (Algal Inhibition test)
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
456-160-0
EC Name:
-
Cas Number:
73942-87-7
Molecular formula:
C12H13NO3
IUPAC Name:
7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:
static
Limit test:
yes
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 29.8 mg/L
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 29.8 mg/L
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
>= 29.8 mg/L
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
>= 29.8 mg/L
Basis for effect:
biomass

Applicant's summary and conclusion

Conclusions:
Under our experimental conditions, the 72h ErC50 and the 72h EbC50 of Veralactame in a static test system were >29,8 mg/L (geometric mean of measured concentrations during the test in a saturated solution obtained from a loading rate of 1000mg/L) for Scenedesmus subspicatus.
The NOEC at 72h was >= 29.8mg/L based on the specific growth rate and biomass data.