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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

NOEC (14d) = 18 mg/L (activated sludge; OECD 301B)

Key value for chemical safety assessment

Additional information

Since no studies on the toxicity to aquatic microorganisms are available a ready biodegradability study is used to derive a NOEC for the toxicity to aquatic microorganisms. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2012b).

Percentage biodegradation in the toxicity controls of an OECD 301B test using 18 mg/L test material on Day 14 was 39% and 14% in two experiments, respectively, thus only in experiment 1 the 25% threshold for inhibition was met (Desmares-Koopmans, 2013). However, one of the test bottles reached 60% biodegradation, which indicated that the test substance did not inhibit microbial activity. Therefore it was concluded, that Multi constituent ester of pentaerythritol 2-ethylhexanoate was found not to inhibit microbial activity.