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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Ecotoxicological information

Toxicity to microorganisms

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Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1996
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given: comparable to guideline studies (2d: Meets national standard methods with acceptable restrictions)
Qualifier:
according to guideline
Guideline:
other: DIN 38 412 part 34
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
yes
Details on test solutions:
Dosage of the test item in ethanolic solution (2 µL/1 mL). Control measurements of solvent controls (test medium with 0.2% ethanol) didn't show any effect.
Test organisms (species):
Photobacterium phosphoreum
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
30 min
Nominal and measured concentrations:
amount of dosed test item (µL pure test item/L test medium): 5, 10, 50, 100, 200, 250, 400, 600
test item concentrations (mg/L) in the study: 4.68, 9.36, 46.8, 93.6, 187.2, 234, 374.4, 561.6
Reference substance (positive control):
no
Duration:
30 min
Dose descriptor:
other: EC20
Effect conc.:
230 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: inhibition of light emission
Remarks on result:
other: interpolated value
Details on results:
mean values of duplicate measurements are reported;
deviation of the duplicate measurements from the mean value was always <3%;
fK value for all determinations between 0.6 and 1.3
Reported statistics and error estimates:
interpolation of the reported EC20 value

test item concentrations (mg/L) in the study (a) and the resulting measured effect (% inhibition of light emission) (b):

(a) 4.68, 9.36, 46.8, 93.6, 187.2, 234, 374.4, 561.6

(b) 7.7, 10.7, 14.1, 13.9, 16.4, 20.6, 18.5, 27.8

Validity criteria fulfilled:
not specified
Conclusions:
The EC20 value for the inhibition of the light emission of Photobacterium phosphoreum after 30 min of incubation to the test substance was determined to be 230 mg/L.
Executive summary:

The purpose of this study was to determine the toxicity of the test substance to bacteria according to DIN 38 412, part 34.

The EC20 value for the inhibition of the light emission of Photobacterium phosphoreum after 30 min of incubation to the test substance was determined to be 230 mg/L (interpolated value).

Description of key information

The toxicity of the test substance Reaction mass of iso-tridecyl 3-mercaptopropionate and iso-dodecyl 3-mercaptopropionate towards the bacterium Photobacterium phosphoreum was determined in a laboratory study according to DIN 38 412, part 34.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
230 mg/L

Additional information

The EC20 value for the inhibition of the light emission of Photobacterium phosphoreum after 30 min of incubation to the test substance Reaction mass of iso-tridecyl 3-mercaptopropionate and iso-dodecyl 3-mercaptopropionate was determined to be 230 mg/L (interpolated value).