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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

log Kow (constituents of the substance): >7.2 at 35°C and pH 7.3 (read-across)
log Kow (constituents): 6.58 - >9.0 at 20°C (QSAR)

Key value for chemical safety assessment

Additional information

There are no reliable measured n-octanol/water partition coefficient data for the registration substance. However, reliable data are available for related substances in the relevant carbon number range.

In OECD 117 studies using the HPLC method, which were conducted in compliance with GLP, Hydrocarbons, C15-C19, n-alkanes, isoalkanes, <2% aromatics (GS270) and Hydrocarbons, C18-C24, isoalkanes, <2% aromatics (GS310) had measured Kow value of >1.58 x 107 (log10Kow >7.2) at 35°C and pH 7.3. The results are considered to be reliable and are used as weight of evidence.

The measured log Kow study is supported by predicted log Kow for individual constituents of the submission substance. The log Kow of each constituent has been predicted using a separately validated QSAR estimation method. The prediction method uses a fragment method and log Kow increases with increasing carbon number. The prediction domain covers carbon chain length in the range C1-C18 carbon atom, it is therefore expected that log Kow for longer chain length (i.e. greater than C18) compounds will be greater than the predicted value of 9.18. The individual constituents of the substance have predicted log Kow values in the range 6.58 - >9 at 20°C.