Registration Dossier
Registration Dossier
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EC number: 609-106-7 | CAS number: 35249-89-9
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study results have been reported in a review and it was not possible to evaluate the original study.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- SCREENING-LEVEL HAZARD CHARACTERIZATION - Glycolic Acid (CASRN 79-14-1). Hazard Characterization Document
- Author:
- U.S. Environmental Protection Agency
- Year:
- 2 010
- Bibliographic source:
- U.S. Environmental Protection Agency
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Water fleas (Daphnia magna; 5/replicate, 4 replicates/concentration) were exposed to CASRN 79-14-1 at nominal concentrations of 0, 25, 50, 100, 200, 400 or 800 mg/L for 48 hours under static conditions.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Glycollic acid
- EC Number:
- 201-180-5
- EC Name:
- Glycollic acid
- Cas Number:
- 79-14-1
- Molecular formula:
- C2H4O3
- IUPAC Name:
- glycol acid
- Reference substance name:
- 2-hydroxyacetic acid
- IUPAC Name:
- 2-hydroxyacetic acid
- Reference substance name:
- Glycolic Acid
- IUPAC Name:
- Glycolic Acid
- Test material form:
- not specified
Constituent 1
Constituent 2
Constituent 3
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- not specified
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 141 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Daphnia magna 48-h EC50 = 141 mg/L.
- Executive summary:
Water fleas (Daphnia magna; 5/replicate, 4 replicates/concentration) were exposed to glycolic acid at nominal concentrations of 0, 25, 50, 100, 200, 400 or 800 mg/L for 48 hours under static conditions. There were no sublethal effects observed in the surviving daphnids.
48-h EC50= 141 mg/L
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