Registration Dossier

Physical & Chemical properties

Water solubility

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Description of key information

The water solubility of this substance is less than 1mg/l and as such for the purposes of REACH can be considered insoluble.

Key value for chemical safety assessment

Water solubility:
0.67 mg/L
at the temperature of:
20 °C

Additional information

The substance under consideration in this dossier does not strictly speaking dissolve in water, some material may be leached from the glass structure. Any gravimetric estimation of weight loss in water is complicated by fibres being retained at the meniscus by surface tension effect and adherence to any glass surface, so that recovery rarely exceeds 90%, in addition to this, the test method used for this study is not ideally suited to the substance being tested and as such there is a large degree of variability between the different results obtained.

Fibres of this type are sometimes described as bio-soluble as they clear rapidly from the lung. A more correct term would be low bio-persistence as they are not dissolved in the lungs, rather they break and the fragments are cleared by the normal physiological method (Moore M, Brown R.C., Pigott G, 2001, Material Properties of MMVF and their time dependant failure in lung environments, Inhalation Toxicology, Vol. 11, pages 1117 - 1149). Thus the description as bio-soluble is erroneous and only used to distinguish these fibres from those that resist lung clearance.

Any materials leaching from the fibres are ubiquitous and non-toxic,