Potassium aluminium silicate amorphous glass fibres

Health surveillance data

Administrative data

Endpoint:

health surveillance data

Type of information:

migrated information: read-across based on grouping of substances (category approach)

Adequacy of study:

weight of evidence

Study period:

Jan 2002 - February 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: a small study carried out using a large proportion of the working population, a deficiency was that the study only considered workers in the UK factories of the study sponsors.

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2002

Report date:

2002

Materials and methods

Study type:

medical screening

Endpoint addressed:

skin sensitisation

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

clinical examination of workforce by expert dermatologist

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide

EC Number:

610-130-5

Cas Number:

436083-99-7

Molecular formula:

Amorphous glass consisting of SinO(3n-1)2(n-1) Polymeric anions ionically bonded to Ca2+ and Mg2+ cations or other alkaline earth cations

IUPAC Name:

amporphous glass fibre formed from the melting and fiberisation of predominately slilcon dioxide, calcium oxide, magnesium oxide

Details on test material:

- Name of test material (as cited in study report): Isofrax, Carbawool(sic)

Method

Type of population:

occupational

Ethical approval:

confirmed, but no further information available

Details on study design:

questionnaire and full clinical examination

Results and discussion

Any other information on results incl. tables

table 2: skin disease findings

Incidental Finding of skin disease amongst those not complaining of skin problems:
*	Contact Dermatitis under Leather Watch Strap
*	Viral wart right index finger
*	Mild pityriasis capitis
*	pityrosporum folliculitis in scalp body and limbs
*	keratosis pilaris on the arms and lymphoedema of leg post DVT
*	Seborrhoeic dermatitis of face chest and scalp
*	Blue naevus in the scalp/organoid naevus in the scalp
*	multiple naevi
*	plantar wart right heel
*	two warts right hand
*	skin tag in axillae
*	skin tags in axillae and neck

 

Table 3: profile of when itch first started

Site	Duration	Findings on Examination
Arms/Face	Few Days	Nil
Arms	Few Days	Nil
Neck Arms Face	2 to 3 weeks	Nil
Face Arms	2 to 3 weeks	Nil
Forearms	2 months	Psoriasis
Neck Arms Legs	2 weeks	Acne