Registration Dossier
Registration Dossier
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EC number: 424-820-7 | CAS number: -
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
Description of key information
The registration substance was miscible in the standard fat (solubility = 937 g test substance/kg standard fat).
Key value for chemical safety assessment
- Solubility in mg/100g standard fat:
- 93 700
- At the temperature of:
- 20 °C
Additional information
The fat solubility of the registration substance was determined according to OECD guideline 116 "Fat solubility of solid and liquid substances, Flask Method".
Fat solubility can be used to evaluate the storage or migration potential of the registration substance into biological tissue. Since natural fats and oils will vary in their composition, a customized, synthetic fat is used to standardize results between laboratories. A preliminary test is used to estimate the solubility of the registration substance at 37 degrees centigrade. A definitive test is then used to establish the solubility of the registration substance in standard fat and show the repeatability of the results over a temperature range of 30 degrees centigrade to 50 degrees centigrade and over a period of approximately 3 to 24 hours.
The registration substance was miscible in the standard fat (i.e. solubility = 937 g test substance/kg standard fat).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
