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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
RTECS Number : PC1210000
Author:
RTECS Database
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances) :Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 46,S1,2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Standard Draize test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
EC Number:
226-501-6
EC Name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
Cas Number:
5413-60-5
Molecular formula:
C12H16O2
IUPAC Name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
Test material form:
gas under pressure: refrigerated liquefied gas
Details on test material:
- Name of test material (as cited in study report): 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Substance type: Organic
- Physical state: Liquid

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Controls:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Reversibility:
not specified
Remarks on result:
other: Dose data : 6.25% , Moderately irritating

Applicant's summary and conclusion

Interpretation of results:
moderately irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is moderately irritating to rabbit eye at dose conc. of 6.25% .
Executive summary:

3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is moderately irritating to rabbit eye at dose conc. of 6.25% .

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