Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2015-10-13 to 2015-11-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
24 August 2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
August 1996
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
20 °C
Vapour pressure:
0.001 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0.001 Pa

The vapour pressure of the test item SIKA Hardener LH was determined at four different temperatures (30, 45, 60 and 75 °C) following EU A.4 using the effusion method (weight loss). Experiment 4 (temperature 75 °C) showed clear signs of decomposition and to avoid bias, these measurements were not used for calculations.
Three experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good to medium reproducibility, giving a good correlation.


The following vapour pressures were determined experimentally and considered as valid (mean and standard deviation given):


Table 2. Experimentally Determined Vapour Pressures









































T



T



P



Stand. Dev. P



RSD P



°C



K



Pa



Pa



%



30.0



303.2



1.84E-03



2.93E-04



15.9%



45.0



318.2



5.72E-03



4.08E-04



7.1%



60.0



333.2



1.46E-02



4.58E-03



31.4%



Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation


 The linear regression of log P vs. 1/T gave a correlation coefficient r of - 0.9996, showing good repeatability and precision. Therefore, the determination is considered as valid. For the test item, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:


 














Vapour pressure at 20 °C:



8.51*10-04 Pa



Vapour pressure at 25 °C:



1.27*10-03 Pa



 

Conclusions:
The estimated vapour pressure of the test item at 20 °C is 8.51E-4 Pa and at 25 °C is 1.27E-3 Pa, respectively.
Executive summary:

The vapour pressure of test item has been determined according to the effusion method described in OECD Guideline n. 104 and EU Regulation No 761/2009, Method A.4. The method is based on the estimation of the mass of test item flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of effused vapour was obtained by determining the loss of mass of the cell. The vapour pressure was calculated by applying the Hertz-Knudsen relation. The vapour pressure of the test item was determined at four different temperatures (30, 45, 60 and 75 °C). The vapour pressures at 20 and 25 °C were calculated from the linear regression equation to be 8.51E-4 and 1.27E-3 Pa, respectively.

Description of key information

The estimated vapour pressure of the test item at 20 °C is 8.51E-4 Pa and at 25 °C is 1.27E-3 Pa, respectively.

Key value for chemical safety assessment

Vapour pressure:
0.001 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of test item has been determined according to the effusion method described in OECD Guideline n. 104 and EU Regulation No 761/2009, Method A.4. The method is based on the estimation of the mass of test item flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of effused vapour was obtained by determining the loss of mass of the cell. The vapour pressure was calculated by applying the Hertz-Knudsen relation. The vapour pressure of the test item was determined at four different temperatures (30, 45, 60 and 75 °C). The estimated vapour pressure of the test item at 20 °C is 8.51E-4 Pa and at 25 °C is 1.27E-3 Pa, respectively.

Categories Display