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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1985
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: - EEC Directive 84/449/EWG, A.7
GLP compliance:
yes
Key result
Medium:
standard fat
Remarks:
HB 307, batch 22
Solubility:
> 400 000 mg/100 g solvent
Temp.:
37 °C
Test substance stable:
yes

In the preliminary test at 37°C, the test substance proved to be fully miscible with fat in the tested concentration range from 104 to 400,000 mg/100 g of solvent.

As no phase separation occurred, the virtual fat solubility test was not performed.

Conclusions:
The fat solubility of test substance was determined to be >400g/100g of solvent at 37°C

Description of key information

The fat solubility of the test substance was determined to be >400g/100g of solvent at 37°C

Key value for chemical safety assessment

Solubility in mg/100g standard fat:
400 000
At the temperature of:
37 °C

Additional information