Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
terrestrial toxicity (Earthworm) by ECOSAR Version 1.10
Author:
ECOSAR Version 1.10
Year:
2012
Bibliographic source:
ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
ECOSAR Program (v1.00)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N-dimethyl-p-toluidine
EC Number:
202-805-4
EC Name:
N,N-dimethyl-p-toluidine
Cas Number:
99-97-8
Molecular formula:
C9H13N
IUPAC Name:
N,N,4-trimethylaniline
Details on test material:
- Name of test material: N,N-dimethyl-p-toluidine
- Molecular formula: C9H13N
- Substance type: Organic
- Physical state: Liquid

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Earthworm
Animal group:
annelids

Study design

Study type:
other: no data
Substrate type:
not specified
Limit test:
yes
Total exposure duration:
14 d

Test conditions

Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
198.045 other: mg/L (ppm)
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The 14 day toxicity (LC50) to earthworm by N,N-dimethyl-p-toluidine as estimated by the ECOSAR model was 198.045 mg/L.
Executive summary:

The 14 day toxicity (LC50) to earthworm by N,N-dimethyl-p-toluidine as estimated by the ECOSAR model was 198.045 mg/L.