Registration Dossier
Registration Dossier
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EC number: 410-560-1 | CAS number: 153519-44-9 CGL 400
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish. No acute toxic effects occur within the range of water solubility.
Key value for chemical safety assessment
Additional information
A GLP guideline according to OECD 203 with zebrafish has been conducted (CIBA-GEIGY Ltd. 1991c). Since the test substance has a very low water solubility an emulsifier has been used. The test substance was homogeneously distributed in the stock solution by mean of NMP, but precipitated when in contact with testwater due to its bad hydrosolubility. This could explain the overall low recoveries found at the start and at the end of exposure. However, no acute toxic effects occurred within the range of water solubility. Additionally, no abnormal effects and symptoms in swimming behaviour, loss of equilibrium, respiratory function, exophtalmus and pigmentation could be observed within all test concentrations up to 96h. Therefore, the test substance is with high probability acutely not harmful to fish.
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