5,5'-Bi-2H-tetrazole, ammonium salt (1:2)

Acute Toxicity: dermal

Administrative data

Endpoint:

acute toxicity: dermal

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2008

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 402 (Acute Dermal Toxicity)

Version / remarks:

92/69/EWG, B.3; OECD 402 (1987)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test type:

fixed dose procedure

Limit test:

yes

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

485-290-0

EC Name:

-

Cas Number:

3021-02-1

Molecular formula:

C2H8N10

IUPAC Name:

5-(1H-1,2,3,4-tetrazol-5-yl)-1H-1,2,3,4-tetrazole diamine

Test animals

Species:

rat

Strain:

Sprague-Dawley

Sex:

male/female

Administration / exposure

Type of coverage:

semiocclusive

Vehicle:

other: ditilled water

Duration of exposure:

24 h

Doses:

2,000 mg/kg

No. of animals per sex per dose:

5

Control animals:

other: historical group

Results and discussion

Effect levels

Sex:

male/female

Dose descriptor:

LD50

Effect level:

> 2 000 mg/kg bw

Mortality:

Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0

Clinical signs:

other: Signs of toxicity related to dose levels: No systemic clinical signs related to the administration of the test item were observed.

Gross pathology:

Effects on organs:
No effects on oragns related to the administration of the
test item were observed.

Other findings:

Signs of toxicity (local):
No cutaneous reactions related to the administration of the
test item were observed.

Applicant's summary and conclusion

Interpretation of results:

not classified

Remarks:

Migrated information Criteria used for interpretation of results: EU