Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute toxicity:
Oral - LD50 = 2171 mg/kg body weight
Dermal - LD50 = >2000mg/kg body weight
Inhalation - LC50 = > 5.83 mg/L air

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 171 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
5.83 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Acute oral toxicity has been investigated using OECD/EU test methods. The median lethal dose (LD50) of the substance following administration of a single oral dose to the rat is 2171 mg/kg body weight.

Acute dermal toxicity has been investigated using OECD/EU test methods. The median lethal dose (LD50) of the substance following administration of a single dermal dose to the rat for a 24 hour period is > 2000 mg/kg body weight

Acute inhalation toxicity has been investigated in accordance with OECD/EU test methods. Rats were exposed for 4 hours to an atmosphere containing the highest achievable concentration that could be generated. The percentage of particles < 4.6 um was in excess of 60%. The median lethal dose (LC50) in the rat was >5.83 mg/L air.

Justification for classification or non-classification

Effects observed following acute exposure by the oral, dermal and inhalation routes at critical concentration / exposure levels are not sufficient to justify classification