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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 15-18, 1986
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1987
Report date:
1987

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EPA primary eye irritation in rabbits (Draize eye irritation) (40 CFR section 798.4500)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
419-690-3
EC Name:
-
Cas Number:
88020-55-7
Molecular formula:
[(C12H25)3NH]4Mo8O26
IUPAC Name:
tridodecylamine hydrate molybdenum

Test animals / tissue source

Species:
rabbit
Strain:
other: New Zealander albino rabbits

Test system

Vehicle:
not specified
Amount / concentration applied:
100 MG
Observation period (in vivo):
1-24-48-72 hours
Number of animals or in vitro replicates:
6 rabbits (young adults)

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
conjunctivae score
Remarks:
(redness)
Basis:
mean
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0 h; Max. value at end of observation period: 0
Irritation parameter:
chemosis score
Basis:
mean
Score:
0
Max. score:
1
Remarks on result:
other: Max. duration: 24 h; Max. value at end of observation period: 0
Irritation parameter:
cornea opacity score
Basis:
mean
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0 h; Max. value at end of observation period: 0
Irritation parameter:
iris score
Basis:
mean
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0 h; Max. value at end of observation period: 0
Other effects:
none

Any other information on results incl. tables

Overall results (showing individual scores if <= 3 animals) calculated on the basis of the scores for each animal at 24, 48, and 72 hours.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information
Conclusions:
Not classified