Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sediment toxicity: short-term
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No sufficient information was available to evaluate the validity of this study. No information was available about the test substance and the test conditions.

Data source

Reference
Reference Type:
publication
Title:
Effect of chlorinated phenol derivatives on various cell models
Author:
Cernakova M.
Year:
1994
Bibliographic source:
Folia Microbiol, 39(4): 315-320

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Guaiacol
EC Number:
201-964-7
EC Name:
Guaiacol
Cas Number:
90-05-1
Molecular formula:
C7H8O2
IUPAC Name:
Phenol
Details on test material:
It was prepared at the Department of Wood, Pulp and Paper, Faculty of Chemical Technology, Slovak Technical University, Bratislava.

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
yes

Test organisms

Test organisms (species):
Tubifex tubifex

Study design

Study type:
other: no data
Test type:
not specified
Water media type:
not specified
Type of sediment:
not specified
Exposure duration
Duration:
45 min
Exposure phase:
total exposure duration

Test conditions

Details on test conditions:
The test substance was diluted in 1.4-dioxane at a concentration of 0.1 g/L. The test substance was evaluated versus the unaffected control, control with 1.4-dioxane, and the positive control represented by benzo[a]pyrene.
No complementary information was available about the test condition and the test design.
Reference substance (positive control):
yes
Remarks:
benzo[a]pyrene

Results and discussion

Effect concentrationsopen allclose all
Duration:
25 min
Dose descriptor:
LD50
Effect conc.:
100 mg/L
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
45 min
Dose descriptor:
LD100
Effect conc.:
100 mg/L
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
No mortality was observed in the control with 1.4-dioxane and in the control uninfluenced.

Applicant's summary and conclusion