Substance Information
Substance Information
REACH Registration data can be found in the new ECHA CHEM database. The old ‘Registered substance factsheets’ will be available on this web site during the transition period but have not been updated since 19 May 2023. More
Diarsenic trioxide
EC / List no.: 215-481-4
CAS no.: 1327-53-3
Mol. formula: As2O3
Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is fatal if swallowed, causes severe skin burns and eye damage, may cause cancer, is very toxic to aquatic life and is very toxic to aquatic life with long lasting effects.
Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may damage fertility or the unborn child, causes damage to organs through prolonged or repeated exposure, is suspected of causing genetic defects, may cause an allergic skin reaction and may cause allergy or asthma symptoms or breathing difficulties if inhaled.
At least one company has indicated that the substance classification is affected by impurities or additives.
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Carcinogenic |
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A majority of data submitters agree this substance is Toxic to Reproduction |
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Some data submitters indicate they consider this substance as Skin sensitising |
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Some data submitters indicate they consider this substance as Respiratory sensitising |
- Substance of very high concern (SVHC) and included in the candidate list for authorisation.
- Substance of very high concern requiring authorisation before it is used (Annex XIV of REACH).
- Some uses of this substance are restricted under Annex XVII of REACH.
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
This substance is used at industrial sites and in manufacturing.
This substance is used at industrial sites and in manufacturing.
Consumer Uses
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Article service life
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using this substance. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Uses at industrial sites
This substance is used in the following products:
metals and
semiconductors.
This substance has
an industrial use resulting in manufacture of another substance (use of intermediates).
This substance is used for the manufacture of:
metals,
mineral products (e.g. plasters, cement) and
chemicals.
Release to the environment of this substance can occur from industrial use:
as an intermediate step in further manufacturing of another substance (use of intermediates),
manufacturing of the substance and
of substances in closed systems with minimal release.
Manufacture
Release to the environment of this substance can occur from industrial use:
manufacturing of the substance,
of substances in closed systems with minimal release and
as an intermediate step in further manufacturing of another substance (use of intermediates).
The InfoCard summarises the non-confidential data on substances as held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The InfoCard is automatically generated. Information requirements under different legislative frameworks may therefore not be up–to–date or complete. Substance manufacturers and importers are responsible for consulting official publications. This InfoCard is covered by the ECHA Legal Disclaimer.
about INFOCARD - Last updated: 06/09/2023