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EC number: 208-031-3 | CAS number: 506-30-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of Eicosanoic acid in aquatic invertebrate [Daphnia magna] in a 48 hr study on the basis of mortality effect was estimated to be 5.7 mg/L. Based on this LC50 value,the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit toxicity to aquatic invertebrate (Daphnia magna) i.e. it is non hazardous to the aquatic environment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5.7 mg/L
Additional information
Based on weight of evidence approach the no.of studies were reviewed for short-term toxicity to aquatic invertebrates from reliable sources having Klimish rating 2 and 4.
The summary of the results are presented below
Sr. No |
Endpoint |
Value |
Duration |
Basis of effect |
Species |
Sources |
1. |
LC50 |
5.7 mg/L |
48 hr. |
Mortality |
Daphnia magna |
Predicted data from QSAR for CAS : 506-30-9 |
2. |
EC50 |
1.22 mg/L |
48 hr. |
Immobilization |
Daphnia magna |
Predicted data from QSAR for CAS : 506-30-9 |
3. |
EC50 |
>5 mg/L |
48 hr. |
Immobilization |
Daphnia magna |
Experimental data from study report for RA CAS : 112-85-6 |
4. |
LC50 |
40 mg/L |
3 hr |
Mortality |
Daphnia pulex |
Experimental data for RA CAS : 8002-13-9 |
Based on the studies summarized in the above table for the target substance Eicosanoic acid and the read across substance,the endpoint value was found to vary between lethal concentration (LC50) = 5.7 mg/L to 40 mg/L and effective concentration (EC50) = 1.22 mg/L to >5 mg/L in a 3 hrs. to 48 hrs.study on the basis of mortality and immobilization effect. Based on the LC50 and EC50 values, ,the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit toxicity to aquatic invertebrate (Daphnia magna and Daphnia pulex ) i.e. it is non hazardous to the aquatic environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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