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EC number: 200-539-3 | CAS number: 62-53-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Pimephales promelas: NOEC = 0.39 mg/L
Key value for chemical safety assessment
Additional information
The lowest, valid NOEC was derived from a study by Russom and Broderius (1991). The authors conducted early-life stage studies with Pimephales promelas with a variety of chemical substances, among them aniline. Embryos < 24 h old were exposed in a flow-through system to aniline for 32 days. The test substance concentration was measured at least twice a week. Test endpoints included percentage of normal larvae at hatch, percent survival and growth effects. A "chronic value", i.e the geometric mean of the NOEC and the LOEC, of 0.557 mg/I was found for the most sensitive endpoint, wet weight and total length. From this a NOEC of 0.39 mg/l can be derived according to the TGD.
A 28-day early-life-stage test with Brachydanio rerio was conducted by van Leeuwen et al. (1990). Fertilised eggs were exposed to aniline in a semistatic manner about 1 day after spawning. Test solutions were renewed three times a week. The actual aniline concentration was analysed before and after renewal of the test solution. It was found that the measured aniline concentrations were far below the nominal concentrations. A 28-day NOEC of 1.8 mg/1 for survival, hatching and growth and a 28-day NOLC (no observed lethal concentration) of 5.6 mg/l was found. Both values are based on nominal concentrations and are therefore not highly reliable. As no further information is given on the measured aniline concentration it is not possible to take into account the decreasing of the substance for the interpretation of the results. Therefore the NOEC from this study cannot be used for the effects assessment.
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