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EC number: 267-022-2 | CAS number: 67762-53-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: 71.9 - 99.8% (CO2 evolution, O2 consumption) after 28 d (OECD 301B, 301F)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Since no studies investigating the ready biodegradability offatty acids, C5-9 tetraesters with pentaerythritol (CAS 67762-35-2)are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to structurally related category membersdecanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid(CAS 71010-76-9),fatty acids, C16-18 and C18-unsaturated, tetraesters with pentaerythritol(CAS 68604-44-4) andpentaerytritol tetraoleate(CAS 19321-40-5) was conducted. The read-across substances are characterized by the same alcohol component (pentaerythritol) tetra-esterified with similar fatty acids (C5-C10) or with longer fatty acids (C16 and C18) and can therefore be used for read-across – in the latter caseas worst case approachsince the chain length is the determining factor for biodegradation. The first step of biodegradation is the enzyme-catalysed cleavage of the ester bond by lipase or esterase which are synthesized by a wide range of microorganisms (Boczar et al., 2001). The free fatty acids (C4 to C24 incl. C18 unsatd.) are known to be degraded rapidly and utilized as substrates by activated sludge microorganisms (Kangala & Medrzycka, 2008). The first study was conducted with decanoic acid, mixed esters with heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS 71010-76-9) (Febbo, 2006). This study was conducted according to OECD 301F (GLP) under aerobic conditions using fresh activated, non-adapted sludge from a municipal sewage treatment plant (STP) as inoculum. A test concentration of 50.2 mg/L (test material) was applied. A mean biodegradation of 84% based on O2 consumption was observed after 28 d. Since the substance reached the pass level for OECD 301F (biodegradation is > 60% after 28 d) the substance is stated to be readily biodegradable according to the OECD criteria.
The second study was conducted withfatty acids, C16-18 and C18-unsaturated, tetraesters with pentaerythritol(CAS 68604-44-4) according to OECD Guideline 301B under aerobic conditions using using non-adapted activated sludge as inoculum (Häner, 2007). A test concentration of 22.8 mg/L (TOC) was applied. Based on CO2 evolution a mean biodegradation of 76% was observed after 28 days. Hence, the substance is determined to be readily biodegradable according to OECD criteria.
These results are supported by a third GLP-Guideline study with pentaerythritol tetraoleate (CAS-No. 19321-40-5) according to OECD 301B using non-adapted activated sludge as inoculum (Desmares-Koopmans, 1997). A test item concentration of 15.6 mg/L was applied. Based on CO2 evolution biodegradation was observed to be in the range of 71.9 to 99.8 after 28 days. Hence, the substance is determined to be readily biodegradable according to OECD criteria.
In addition, results from QSAR calculations (BIOWIN v4.10) for the main components offatty acids, C5-9 tetraesters with pentaerythritol (CAS 67762-35-2)indicate, that the substance is readily biodegradable (Hopp, 2011).
Based on the results from structurally related read-across substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) and on the results from QSAR calculations for the main components it can be concluded thatfatty acids, C5-9 tetraesters with pentaerythritol (CAS 67762-35-2)is readily biodegradable according to the OECD criteria.
A detailed reference list is provided in the technical dossier (see IUCLID, section 13) and within CSR
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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