Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-859-9 | CAS number: 100-51-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://chesar.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Long-term toxicity to fish
Administrative data
- Endpoint:
- long-term toxicity to fish, other
- Remarks:
- (Q)SAR calculated endpoint
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: US EPA accepted QSAR method for chemicals properties assessment.
The substance is readily biodegradable and considered to be of low risk to fish.
Data source
Reference
- Reference Type:
- other: QSAR model
- Title:
- EPI Suite v 4.0/ECOSAR v1.00
- Author:
- US EPA
- Year:
- 2 014
- Bibliographic source:
- http://epa.gov/oppt/exposure/pubs/episuite.htm
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- ECOSAR Program (v1.00)
- GLP compliance:
- no
- Remarks:
- not applicable to QSAR models
Test material
- Reference substance name:
- Benzyl alcohol
- EC Number:
- 202-859-9
- EC Name:
- Benzyl alcohol
- Cas Number:
- 100-51-6
- Molecular formula:
- C7H8O
- IUPAC Name:
- phenylmethanol
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not required
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- other: Fish species
- Details on test organisms:
- no further information
Study design
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 d
Test conditions
- Hardness:
- not applicable. QSAR model
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Dissolved oxygen:
- not applicable. QSAR model
- Salinity:
- not applicable. QSAR model
- Details on test conditions:
- SMILES : OCc(cccc1)c1
CHEM : Benzenemethanol
CAS Num: 100-51-6
MOL FOR: C7 H8 O1
MOL WT : 108.14
Log Kow: 1.08 (KowWin estimate)
Wat Sol: 4.29E+004 mg/L (experimental database) - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 48.897 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: non-toxic , as determined by (Q)SAR
- Details on results:
- A NOEC value of 48.897 mg/L has been calculated for the effects of the test substance on the mortality of the fish taxonomic group. This result signifies that the test substance is not expected to be toxic .
Any other information on results incl. tables
Overview of QSARs estimations onlong-term aquatic toxicity of benzyl alcohol to fish
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Fish, 96-hr LC50 =504.664 mg/L (ppm) Fish 30-day ChV = 48.897 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Fish, 96-hr LC50 =504.664mg/L (ppm)
Fish 30-day ChV =48.897mg/L (ppm)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- A NOEC value of 48.897 mg/L has been calculated for the effects of the test substance on the mortality of the fish taxonomic group. This result signifies that the test substance is not expected to be toxic .
- Executive summary:
The ECOSAR QSAR model predicts that the NOEC for freshwater fish would to be 48.897 mg/l .This result signifies that the test substance is not expected to be toxic .
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)