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Diss Factsheets
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EC number: 212-344-0 | CAS number: 793-24-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other:
- Adequacy of study:
- supporting study
- Study period:
- 2012
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- The MAK Collection for Occupational Health and Safety; N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylendiamin (6-PPD) [MAK Value Documentation in German language, 2013]
- Author:
- Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area
- Year:
- 2 012
- Bibliographic source:
- MAK Value Documentation, Published Online: 22 MAY 2013; http://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb79324d0055/abstract
Materials and methods
- Type of study / information:
- Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Occupational exposure level (MAK-value) derived
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: Comprehensive evaluation of all relevant data
- Principles of method if other than guideline:
- Definition
The MAK value (“maximale Arbeitsplatz-Konzentration”: maximum workplace concentration) is defined as the maximum concentration of a chemical substance (as gas, vapour or particulate matter) in the workplace air which generally does not have known adverse effects on the health of the employee nor cause unreasonable annoyance (e. g. by a nauseous odour) even when the person is repeatedly exposed during long periods, usually for 8 hours daily but assuming on average a 40-hour working week. - GLP compliance:
- no
Test material
- Reference substance name:
- N-1,3-dimethylbutyl-N'-phenyl-p-phenylenediamine
- EC Number:
- 212-344-0
- EC Name:
- N-1,3-dimethylbutyl-N'-phenyl-p-phenylenediamine
- Cas Number:
- 793-24-8
- Molecular formula:
- C18H24N2
- IUPAC Name:
- N1-(4-methylpentan-2-yl)-N4-phenylbenzene-1,4-diamine
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
MAK defined the 8-h TWA (MAK value) to be 2 mg/m3
Exposure can be exceeded by a factor of 2 for short-term exposure
The compound should be regarded as a skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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