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EC number: 288-668-1 | CAS number: 85865-69-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility for Daphnia magna (EU Method C.2)
Key value for chemical safety assessment
Additional information
There are no studies available on the short-term aquatic invertebrate toxicity of Fatty acids, C16-18, isobutyl esters (CAS No. 85865-69-6). The assessment of short-term toxicity was therefore based on studies conducted with the structurally most similar category members, for which data is available, Fatty acids, C16-18, Bu esters (CAS No. 85408-76-0), isopropyl palmitate (CAS No. 142-91-6) and Fatty acids, C16-18 and C18-unsaturated isobutyl esters (CAS No. 84988-79-4). This read across approach is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the category justification in Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substances were entered into IUCLID. Nevertheless, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the hazard assessment for this endpoint, by showing a consistent pattern of results.
The key study with Fatty acids, C16-18, Bu esters (CAS No. 85408-76-0) was performed as a limit test according to EU Method C.2 and GLP (Wierich, 1998). The test organism Daphnia magna was exposed to the test organism in a static system for 48 hours, at the nominal test concentration of 100 mg/L, prepared as water accommodated fractions (WAF). No immobilisation was observed at any treatment, and an EC50 of > 100 mg/L was reported.
The key study with isopropyl palmitate (CAS No. 142-91-6) was performed according to EU Method C.2 and GLP (Kirch, 1998). The test organism Daphnia magna was exposed to the test substance in a static system for 48 hours, at nominal test concentrations of 1000 and 3000 mg/L (measured initial concentrations 0.72 and 1.68 mg/L). No immobility was observed at any of the test concentrations, and the EC50 was reported to be > 3000 mg/L.
The key study conducted with Fatty acids, C16-18 and C18-unsaturated isobutyl esters (CAS No. 84988-79-4) was performed as a limit test according to EU guideline 92/69/EWG and GLP (Wierich, 1995). The test organism Daphnia magna was exposed to the test substance in a static system for 48 hours. Three different methods were applied for the preparation of test solutions: 1) direct addition to nominal 100 mg/L without separation of undissolved test material, 2) direct addition to nominal 100 mg/L followed by a separation of undissolved test material and 3) 3 to 5 fold saturation concentration without separation of undissolved material. Immobilisation was observed only in the test solutions prepared using the first method, and was therefore probably due to physical effects caused by the large amount of undissolved test material present in the test solution. With separation of undissolved test material and with 3 to 5 fold saturation no negative effects were observed. It can be concluded that the test substance had no toxic effects on Daphnia magna up to the limit of water solubility. An EL50 of > 100 mg/L is reported.
Thus, based on theabove mentioned results, and due to the structural and profile similarities of the two substances, as are explained with in the overall endpoint summary 6.1 it can be concluded that no toxicological short-term effects on aquatic invertebrates are expected up tothe limit ofwater solubility for of Fatty acids, C16-18, isobutyl esters (CAS No. 85865-69-6).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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