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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
long-term toxicity to fish
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.

Data source

Reference
Reference Type:
other: SNIF
Title:
Unnamed
Year:
1992

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate
EC Number:
413-750-2
EC Name:
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate
IUPAC Name:
413-750-2
Constituent 2
Reference substance name:
reaction mass of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate
IUPAC Name:
reaction mass of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate
Test material form:
not specified

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Acetone :33 µL/L

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
21 d
Remarks on exposure duration:
Duration is normally 14 days, but can be extended by one or two weeks in accordance with the guideline.

Test conditions

Hardness:
243 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
> 0.33 mg/L
Nominal / measured:
nominal
Conc. based on:
not specified
Basis for effect:
mortality
Duration:
21 d
Dose descriptor:
LC50
Effect conc.:
> 0.33 mg/L
Nominal / measured:
nominal
Conc. based on:
not specified
Basis for effect:
mortality
Duration:
14 d
Dose descriptor:
NOEC
Effect conc.:
0.33 mg/L
Nominal / measured:
nominal
Conc. based on:
not specified
Basis for effect:
not specified
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.33 mg/L
Nominal / measured:
nominal
Conc. based on:
not specified
Basis for effect:
other: visible abnormality
Details on results:
%Concentration loss over test: 19.2 ...
Signs of toxicity: None

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
LC50 (21d) > 0.33 mg/L
NOEC (21d) = 0.33 mg/L
Due to its low water solubility, the test substance is considered not to be toxic to fish under the conditions of the test.