Acetamide, N-[5-[bis[2-(acetyloxy)ethyl]amino]-2-[2-(2-hydroxy-4-nitrophenyl)diazenyl]phenyl]-

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2002

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Test material

Test material information

Constituent 1

Reference substance name:

Red 0106-PP1

IUPAC Name:

Red 0106-PP1

Results and discussion

Water solubility

Water solubility:

< 0.1 mg/L

Temp.:

20 °C

Remarks on result:

other: pH of the solution analyzed not reported

Any other information on results incl. tables

During the main test six samples have been analysed in the first run (0.52 ml/min) and six samples during the second run (0.26 ml/min), each with a sampling interval of one hour. Total elution time was 68.5 hours. The quantification was performed by HPLC. The measured results differ by less than 30 %. Therefore the study is considered to be valid.

The test item could not be detected in any of the eluate samples.

In conclusion, the water solubility of RED 0106-PP1 at 20 °C ± 0.5 °C was determined to be below the limit of determination which is 1 mg/l.

Applicant's summary and conclusion

Conclusions:

Water solubility < 0.1 mg/l at 20 °C