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Diss Factsheets
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EC number: 940-877-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Version / remarks:
- 2000
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.18 (Adsorption / Desorption Using a Batch Equilibrium Method)
- Version / remarks:
- 2001
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Hessisches Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany
- Type of method:
- batch equilibrium method
- Media:
- soil
- Radiolabelling:
- no
- Test temperature:
- 20 °C ± 2 °C
in case of the first adsorption kinetic experiment the temperature was in range of 17 to 20 °C - Analytical monitoring:
- yes
- Details on sampling:
- - Sampling was accomplished applying the parallel method, hence as many samples with the same soil/solution ratio were prepared, as time intervals at which it was desired to study the adsorption behaviour.
- Sampling interval: after 4 h, 24 h and 48 h - Details on matrix:
- Five different soils were initially used which varied in clay content, organic carbon content and pH. The following soils with typical characteristics were used:
Soil A (LUFA 2.1):
sand (pH 5.1, clay content 3.0 %, organic carbon content 0.68 %), origin: LUFA Speyer, Germany
Soil B (LUFA 6S):
clay (pH 7.2, clay content 42 %, organic carbon content 1.75 %), origin: LUFA Speyer, Germany
Soil C (LUFA 2.4):
loam (pH 7.1, clay content 27 %, organic carbon content 2.42 %), origin: LUFA Speyer, Germany
Soil D (EUROSOIL 1):
clay (pH 5.7, clay content 75.0 %, organic carbon content 3.27 %), origin: IRMM Geel, Belgium
Soil E (EUROSOIL 5):
loamy sand (pH 3.1, clay content 6.0 %, organic carbon content 5.96 %); origin: IRMM Geel, Belgium
The tests were run using air-dried fine sieved soil (< 2 mm). The dry weight content of the soil was determined. Soils were not sterilised.
The test soils were chosen based on the guidance/advice given by the OECD 106 guideline. - Details on test conditions:
- TEST CONDITIONS
- Test vessels: The test vessels were made of glass and adsorbed negligible amounts of the test item.
- Buffer: 0.01 M CaCl2 solution
- pH: 3.1 - 7.2
TEST SYSTEM
- Method of preparation of test solution: The stock solution was diluted using 0.01 M CaCl2 to a concentration of 80 mg/L in 0.01 M CaCl2. Aliquots of the 80 mg/L solution were applied to soil.
- Preparation of the test soils: The soil samples were equilibrated by agitating the soil with 4 mL of 0.01 M CaCl2 solution overnight followed by addition of 0.1 mL of the stock solution.
Desorption test:
Preparation of test solutions and test soil was conducted identically to the adsorption test. After the equilibration time of 48 h the solid and liquid phases were separated by centrifugation. The aqueous phase was removed to the greatest extent possible. The volume of CaCl2 removed was replaced by an equal volume of fresh 0.01 M CaCl2. The new mixtures were agitated again and samples were taken applying a parallel method after 4 h, 24 h and 48 h. The aqueous phases were recovered after centrifugation and analysed after filtration over 0.2 μm syringe filters by HPLC coupled with UV detection. - Type:
- Koc
- Value:
- 37.5
- % Org. carbon:
- 0.68
- Remarks on result:
- other: LUFA 2.1 (sand)
- Type:
- log Koc
- Value:
- 1.6
- % Org. carbon:
- 0.68
- Remarks on result:
- other: LUFA 2.1 (sand)
- Type:
- Koc
- Value:
- 4.4
- % Org. carbon:
- 1.72
- Remarks on result:
- other: LUFA 6S (clay)
- Type:
- log Koc
- Value:
- 0.6
- % Org. carbon:
- 1.72
- Remarks on result:
- other: LUFA 6S (clay)
- Type:
- Koc
- Value:
- 12.7
- % Org. carbon:
- 2.42
- Remarks on result:
- other: LUFA 2.4 (loam)
- Type:
- log Koc
- Value:
- 1.1
- % Org. carbon:
- 2.42
- Remarks on result:
- other: LUFA 2.4 (loam)
- Type:
- Koc
- Value:
- 115.7
- % Org. carbon:
- 3.27
- Remarks on result:
- other: Eurosoil 1 (clay)
- Type:
- log Koc
- Value:
- 2.1
- % Org. carbon:
- 3.27
- Remarks on result:
- other: Eurosoil 1 (clay)
- Type:
- Koc
- Value:
- 42.1
- % Org. carbon:
- 5.96
- Remarks on result:
- other: Eurosoil 5 (loamy sand)
- Type:
- log Koc
- Value:
- 1.6
- % Org. carbon:
- 5.96
- Remarks on result:
- other: Eurosoil 5 (loamy sand)
- Adsorption and desorption constants:
- Apparent desorption coefficients:
LUFA 2.1 (sand) -2.5
LUFA 6S (clay) 1.8
LUFA 2.4 (clay) -1.7
Eurosoil (loam)33.4
Eurosoil (loamy sand) 6.2 - Details on results (Batch equilibrium method):
- PRELIMINARY TEST
- Mass balance: 87% to 105%
- Weighed soil: ca. 2 g
- Volume of CaCl2 solution: 5, 10 and 20 mL
- Initial test substance concentration: approx. 10 mg/L
SCREENING TEST - ADSORPTION KINETICS AT ONE CONCENTRATION
- Test material stability during adsorption/desorption phase: Analyses of control samples confirmed that the test item was stable under the test conditions.
Reference
Description of key information
log Koc: 0.6 - 2.1 (OECD 106)
Key value for chemical safety assessment
Additional information
One study is available on the adsorption/desorption behaviour of Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid. The study was conducted according to OECD Guideline 106 and GLP (Meinerling, 2012). Log Koc values of 0.6 - 2.1 were obtained for the five different soils tested.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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