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Diss Factsheets
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EC number: 205-406-3 | CAS number: 140-26-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 2.872 mg/L on fish for substance Phenethyl isovalerate with mortality effects.
But the partition coefficient (log Kow ) value for test substance not ≥ 4 it is found to be in the range 3.71 to 3.9 thus not fulfill the classification criteria of CLP and therefore the target chemical not consider for the aquatic classification.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.872 mg/L
Additional information
Based on the Weight of evidence approch for the target substance Phenethyl isovalerate studies are summarized as fallowed :
Based on the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be 2.872 mg/L on fish for substance Phenethyl isovalerate with mortality effects.
And in second study which is based on the Danish QSAR database, the short term toxicity in fish for 96 hours LC50 was estimated to be 2.38025 mg/L for substance Phenethyl isovalerate with mortality effects.
But the partition coefficient (log Kow ) value for test substance not≥4 it is found to be in the range 3.71 to 3.9 thus not fulfil the classification criteria of CLP and therefore the target chemical not consider for the aquatic classification.
Above conclusion also support by read across chemical (Cas no.140-11-4) study from peer reviewed journal (U.S.Fish.Wildl.Serv., Sp.Sci.Rep; 124 p., 1963) i.e Short term toxicity study to Cyprinus carpio was carried out for 44 hrs. Test was performed under flow through conditions. After exposure of test animal to different dose conc. i.e, at 68, 130 and 146 mg/l of test chemical benzyl acetate, no effects were observed on mobility of the test animal. Thus, the NOEC value was consider to be 146 mg/l respectively.
Overall all studies concluded that the test substance Phenethyl isovalerate is non toxic to aquatic environment thus not consider for the further classification.
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