Registration Dossier
Registration Dossier
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EC number: 202-384-7 | CAS number: 95-02-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24/09/1973
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: scientifically acceptable
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: not applicable
- Deviations:
- not applicable
- Principles of method if other than guideline:
- see below
- GLP compliance:
- no
- Test type:
- other: not specified
- Limit test:
- no
Test material
- Reference substance name:
- 4-amino-2-methylpyrimidine-5-methylamine
- EC Number:
- 202-384-7
- EC Name:
- 4-amino-2-methylpyrimidine-5-methylamine
- Cas Number:
- 95-02-3
- Molecular formula:
- C6H10N4
- IUPAC Name:
- 5-(aminomethyl)-2-methylpyrimidin-4-amine
- Details on test material:
- -
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- not available
- No. of animals per sex per dose:
- 10 per dose
- Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 4 240 mg/kg bw
- 95% CL:
- > 3 570 - < 4 910
- Remarks on result:
- other: after 24 h
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 4 240 mg/kg bw
- 95% CL:
- > 3 570 - < 4 910
- Remarks on result:
- other: after 10 d
Any other information on results incl. tables
no other remarks
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- No classification in the EU required
- Executive summary:
No acute toxicity observed (> 2000 mg/kg BW)
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