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Diss Factsheets
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EC number: 204-854-7 | CAS number: 127-65-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 March 2007 - 27 March 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study performed under GLP and according to OECD guidelines.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Differential scanning calorimetry (DSC) and Capillary Tube in a Metal Block
- Key result
- Decomposition:
- yes
- Decomp. temp.:
- >= 120 - <= 165 °C
- Conclusions:
- Substance has no melting point at atmospheric pressure. It decomposes first at approximately 120-165 ºC.
- Executive summary:
A study was performed under GLP and according to OECD102 using Differential Scanning Calorimetry (DCS) and capillary method (metal block) methods to determine the melting point for Tosylchloramide sodium. Substance has no melting point at atmospheric pressure. It decomposes first at approximately 120-165 ºC.
Reference
Thermal Stability (DSC)
The DSC-measurement in the closed glass crucible showed an endothermic effect in the temperature range 65 - 90 ºC and an exothermal decomposition in the temperature range 120 - 150 ºC.
Melting Point 1 Melting Ranqe (DSC)
The DSC-measurements in aluminium crucibles with a hole showed three endothermic effects (dehydration) in the temperature ranges 70 -90ºC, 105 -135°C and 135 -155ºC and an exothermal decomposition in the temperature range 155 - 165ºC with an energy of 120 J/g. After the DSC-measurement the test item was not melt, it still remained a solid. Three additional measurements with the capillary method were performed to clarify the results of the DSC measurements.
No | set point | heating rate | end point | melting point | remarks |
1 | 60 ºC | 2K/min | 170ºC | - | The test item started to sinter at 80 ºC,133 ºC appearance of gas bubbles,138 ºC arise of the sample,141 ºC sample was arisen out of sight,145 ºC test abortedNo melting was observed over the measurment |
2 | 100ºC | 3K/min | 180ºC | - | 90 ºC test item sintered,123 ºC appearance of gas bubbles, arise of the sample136 ºC higher rate of gas bubbles,140 ºC tube empty, sample evaporated141 ºC test abortedNo melting was observed over the measurement |
3 | 140ºC | 5K/min | 180ºC | - | approx. 100 ºC test item sintered,135 -145 ºC appearance of gas bubbles, arise of thesample150 "C tube empty, sample evaporated153 "C test abortedNo melting was observed over the measurement |
According to the results of both methods it can be stated that the test item has no melting point. The endothermic effects observed in the DSC-measurements correspond to physical transformations of the test item e.g. to changes in the crystalline structure due to a stepwise dehydration of the test item (tri hydrate). The test item decomposes first at approximately 120ºC-165ºC.
Description of key information
Tosylchloramide sodium has no melting point at atmospheric pressure and decomposes at temperatures of 120 - 165ºC. The internal database of EpiSuite also mentions a 170 °C melting point. To conduct the CSA, the higher decomposition temperature will thus be stated as the melting point temperature.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 165 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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