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Diss Factsheets
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EC number: 222-182-2 | CAS number: 3380-34-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Monitoring data
Administrative data
- Endpoint:
- monitoring data
- Type of information:
- other: literature review
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data from multiple sources: Guideline studies (GLP/non-GLP), publications in (peer-reviewed) journals
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
- Reference Type:
- other: Primary sources
- Title:
- No information
- Author:
- Primary sources are listed under "Any other information on material and methods incl. tables"
Materials and methods
- Principles of method if other than guideline:
- A literature search was performed to collect recent information on environmental fate of Triclosan (TCS) and Methyltriclosan (MTCS). The references are listed under "Any other information on materials and methods incl. tables"
Test material
- Reference substance name:
- Triclosan
- EC Number:
- 222-182-2
- EC Name:
- Triclosan
- Cas Number:
- 3380-34-5
- Molecular formula:
- C12H7Cl3O2
- IUPAC Name:
- 5-chloro-2-(2,4-dichlorophenoxy)phenol
Constituent 1
Results and discussion
Any other information on results incl. tables
Environmental monitoring
Environmental concentrations of TCS were analysed in surface waters (fresh and marine waters) of several European countries. The maximum concentrations declined from the period between 1998-2009 to 2010-2012 from 0.285 µg/L to 0.138 µg/L in freshwater and from 0.142 to 0.029 µg/L in marine water.
Environmental concentrations of MTCS were analysed in different media: river and lake waters, wastewater treatment plant (WWTP) effluents, sewage sludges and soils. The maximum concentration detected in river water was 2300 ng/L in a monitoring study over 30 US states including 139 streams (Kolpin et al., 2002). Other data suggest generally lower values with a range of < 2–80 ng/L with higher values downstream of WWTPs (Cheng et al., 2011; Coogan et al., 2007; Waiser et al., 2011). Lake waters contained between 0.1–0.8 ng/L (Andresen et al., 2007; Lindström et al., 2002; Singer et al., 2002). Effluents from WWTPs reached MTCS values of up to 65 ng/L with a range of < 2–65 ng/L (Bester, 2005; Ciba, 1997; Lindström et al., 2002). In sewage sludges a maximum content of 1.03 µg/g dw was detected, although most values were well below this value (0.05–0.45 µg/g dw; McAvoy et al., 2002). The TCS content in these sludges was between 0.53 and 14.7 µg/g dw.
In a field TCS biodegradation soil study by Lozano et al. (2012), control soil contained <= 0.48 ng/g dw MTCS compared to a TCS concentration of 2.7±0.7 ng/g dw. Spanish soil samples contained between 0.3 and 3.8 ng/g dw (Sánchez-Brunete et al., 2010). These values are very low compared to sewage sludge data which showed an MTCS content of 4–311 ng/g dw (Sánchez-Brunete et al., 2010).
Applicant's summary and conclusion
- Conclusions:
- Triclosan and its metabolite methyltriclosan have been detected in the environment during several monitoring studies. Data are mainly available from Europe and the USA.
- Executive summary:
Triclosan and its metabolite methyltriclosan have been detected in the environment during several monitoring studies. Data are mainly available from Europe and the USA. The following media have been analysed: river and lake waters, wastewater treatment plant (WWTP) effluents, sewage sludges and soils.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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