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Diss Factsheets
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EC number: 201-180-5 | CAS number: 79-14-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in air
Administrative data
- Endpoint:
- phototransformation in air
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: The substance was found not to be within the applicability domain of the Atmospheric Oxidation Program v1.90 (AOPWIN) QSAR model and therefore the use of this model to predict atmospheric degradation of the substance cannot be considered valid.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
- Principles of method if other than guideline:
- The calculation (QSAR estimation) was performed using the Atmospheric Oxidation Program v1.90 (AOPWIN). The substance was found not to be within the applicability domain of the Atmospheric Oxidation Program v1.90 (AOPWIN) QSAR model and therefore the use of this model to predict atmospheric degradation of the substance cannot be considered valid.
- GLP compliance:
- no
Test material
- Reference substance name:
- Glycollic acid
- EC Number:
- 201-180-5
- EC Name:
- Glycollic acid
- Cas Number:
- 79-14-1
- Molecular formula:
- C2H4O3
- IUPAC Name:
- 2-hydroxyacetic acid
Constituent 1
Study design
- Estimation method (if used):
- The photochemical oxidative degradation half-life of glycolic acid in air was estimated using the Atmospheric Oxidation Program v1.90 (AOPWIN), which is based on the structural activity relationship (QSAR's) methods developed by Atkinson, R (1985 to 1996).
- Details on light source:
- not applicable
- Details on test conditions:
- not applicable
Results and discussion
- Preliminary study:
- not applicable
Dissipation half-life of parent compound
- DT50:
- 41.247 h
- Test condition:
- The substance was found not to be within the applicability domain of the Atmospheric Oxidation Program v1.90 (AOPWIN) QSAR model and therefore the use of this model to predict atmospheric degradation of the substance cannot be considered valid.
Any other information on results incl. tables
The half life and rate constant for the photochemical oxidative degradation of glycolic acid in air via the hydroxyl reaction was estimated to be 41.247 hours and 3.11 x 10–12 cm3 molecule-1 s-1, respectively (based on 1.5 x 106 OH radicals per cm3) resulting mostly from hydrogen abstraction.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Remarks:
- The substance was found not to be within the applicability domain of the Atmospheric Oxidation Program v1.90 (AOPWIN) QSAR model and therefore the use of this model to predict atmospheric degradation of the substance cannot be considered valid.
- Conclusions:
- Due to the chemical lifetime of glycolic acid in the air (at the most 3.4 days, based on a 12 hour day) it is to be expected that the active substance can not be transported in the gaseous phase over large distances and can not accumulate in the air.
- Executive summary:
The photochemical oxidative degradation half-life of glycolic acid in air was estimated using the Atmospheric Oxidation Program v1.90 (AOPWIN), which is based on the structural activity relationship (QSAR's) methods developed by Atkinson, R (1985 to 1996).
The half life and rate constant for the photochemical oxidative degradation of glycolic acid in air via the hydroxyl reaction was estimated to be 41.247 hours and 3.11 x 10–12cm3molecule-1s-1, respectively (based on 1.5 x 106OH radicals per cm3) resulting mostly from hydrogen abstraction. On the account of the chemical lifetime of glycolic acid in the air (at the most 3.4 days, based on a 12 hour day) it is to be expected that the active substance can not be transported in the gaseous phase over large distances and can not accumulate in the air. Thus, no difference in the behaviour between glycolic acid and other organic substances emitted into the air from natural sources (e.g. plants, soil) is indicated.
Due to the chemical lifetime of glycolic acid in the air (at the most 3.4 days, based on a 12 hour day) it is to be expected that the active substance can not be transported in the gaseous phase over large distances and can not accumulate in the air.
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