Registration Dossier
Registration Dossier
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EC number: 201-202-3 | CAS number: 79-39-0
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Methacrylamide
- EC Number:
- 201-202-3
- EC Name:
- Methacrylamide
- Cas Number:
- 79-39-0
- Molecular formula:
- C4H7NO
- IUPAC Name:
- methacrylamide
- Test material form:
- solid
- Details on test material:
- Batch (Lot) Number: 11110320
Constituent 1
- Specific details on test material used for the study:
- WAKO Pure Chemicals Industries, Ltd. (Lot. PAL0299)
Purity: 99.3%
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- -0.15
- Temp.:
- 25 °C
- pH:
- >= 6.2 - <= 6.3
Any other information on results incl. tables
Results:
LOG POW
-----------------------------------------------------------
Test A B Average
-----------------------------------------------------------
No.1 -0.13 -0.15
(6.3) (6.2)
No.2 -0.17 -0.17 -0.15
(6.2) (6.2)
No.3 -0.13 -0.13 (6.2) (6.2)
-----------------------------------------------------------
() is pH of water layer
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient n-octanol/water was determined according to OECD 107 (Flask-shake method). Log Pow = - 0.15 at 25 °C.
- Executive summary:
The partition coefficient n-octanol/water was determined according to OECD 107 (Flask-shake method). Log Pow = - 0.15 at 25 °C.
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