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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 12, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Lase light scattering as described in SOP - STR 071 (Hydro 2000S) protocol.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
35.807 µm
Percentile:
D10
Mean:
ca. 5.514 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment
Percentile:
D50
Mean:
ca. 35.807 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment
Percentile:
D90
Mean:
ca. 106.783 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment
Conclusions:
D10 = 5.514 µm
D50 = 35.807 µm
D90 = 106.783 µm
Executive summary:

Method:


Particle size distribution was analysed using the Mastersizer 2000 tool. Particles size was measured by the laser diffraction technique, which measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analysed to calculate the size of the particles that created the scattering pattern.


Result:


Analysis carried out after 2 minutes of ultrasonic treatment:


D10 = 5.514 µm


D50 = 35.807 µm


D90 = 106.783 µm

Description of key information

Laser light scattering method - MMD = 35.807 µm

Additional information