Registration Dossier
Registration Dossier
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EC number: 222-872-3 | CAS number: 3644-12-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 983
- Report date:
- 1983
Materials and methods
Test guideline
- Guideline:
- other: "Appraisal of the safety of chemicals in food, drugs and cosmetics", by the staff of the Division of Pharmacology, FDA, 1959
- GLP compliance:
- not specified
Test material
- Reference substance name:
- N-(methoxymethyl)methacrylamide
- EC Number:
- 222-872-3
- EC Name:
- N-(methoxymethyl)methacrylamide
- Cas Number:
- 3644-12-0
- Molecular formula:
- C6H11NO2
- IUPAC Name:
- N-(methoxymethyl)-2-methylacrylamide
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Score:
- 0.6
- Max. score:
- 8
- Reversibility:
- fully reversible
- Remarks on result:
- other: slightly irritating
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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